Bayern said Sane tore the rear thigh muscle in his left leg and did not give a timeline on his return but German media said he would be out for three weeks.
The 26-year-old has been in fine form for the German giants with 10 goals in all competitions this season, including five in his last five games. He contributed with a goal and an assist in the win over Freiburg.
Germany, who are in Group E alongside Spain, Costa Rica and Japan at the Nov 20 – Dec 18 World Cup in Qatar, have yet to announce their final squad. They begin their group campaign on Nov 23 against Japan.
Bayern visit Augsburg in the German Cup on Wednesday, Hoffenheim in the Bundesliga on Saturday and Barcelona in the Champions League next Wednesday.
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