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Five children and a man who lived at the property on Russell Island – about 60km southeast of Brisbane, were unaccounted for after the blaze engulfed the house in the early hours of today.
“Upon arrival, the house was fully involved and multiple surrounding properties were damaged,” police said in a statement.
Queensland Ambulance Service said in a tweet that structures remained on fire and multiple patients were being assessed.
Two people were taken to hospital in a stable condition, it said.
At least 20 firefighters were battling the blaze, the Australian Broadcasting Corporation reported.
Investigations were underway to determine the cause of the fire, police said.
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