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“A total of 10,400kg of cocaine hydrochloride were seized and incinerated,” the head of the country’s anti-drugs agency Richard Lopez said on X, formerly Twitter.
Cocaine hydrochloride refers to the powder form of the illicit drug.
Venezuela confiscated about 51 tons of drugs so far this year, resulting in more than 13,000 arrests, Lopez said.
Police dismantled three cocaine production camps with 13 laboratories, a logistics centre, and a weapons and explosives manufacturing plant, he added.
The official did not report any arrests in the three-day operation in northwestern Zulia state, on the border with Colombia and where most drugs have been seized this year.
More than 41 tons of narcotics were seized in 2022, according to the anti-drugs agency.
Millions have left Venezuela in recent years, as it suffers from an economic crisis that has seen poverty soar, with many settling in Colombia.
The South American nations share a 2,200km border through a region riddled with armed groups contending for lucrative drug trafficking and smuggling routes.
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